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Symbol
Name
ID

Ern1
endoplasmic reticulum to nucleus signalling 1
MGI:1930134

Phenotype annotations related to liver/biliary system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Micronodular cirrhosis	Subacute progressive viral hepatitis	Hepatocellular carcinoma
Disease(s) Associated with ERN1
hepatocellular carcinoma

Mouse Phenotypes		liver/biliary system phenotype	increased hepatocyte apoptosis	increased liver triglyceride level	abnormal hepatocyte morphology	liver hypoplasia	hepatic steatosis
Availability	Mouse Genotype	liver/biliary system phenotype	increased hepatocyte apoptosis	increased liver triglyceride level	abnormal hepatocyte morphology	liver hypoplasia	hepatic steatosis
	Ern1^tm1Rjk/Ern1^tm1Rjk
	Ern1^tm1Rjk/Ern1^tm2.1Rjk Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ (conditional)
	Ern1^tm2.1Tiw/Ern1^tm2.2Tiw Meox2^tm1(cre)Sor/Meox2⁺ (conditional)	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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